Kepa Arrizabalaga is in goal, as he was in the previous round against Aston Villa, and Malang Sarr returns to the back three alongside Reece James and Trevoh Chalobah.

Captain Marcos Alonso comes in at left wing-back, and there is a place in midfield for Saul. Further forward, Hakim Ziyech and Ross Barkley support Kai Havertz in attack.

Harvey Vale, 18, is named among the substitutes for the first time. He has scored five goals for our development squad this season. Academy keeper Teddy Sharman-Lowe is also on the bench.

Chelsea (3-4-3): Kepa; James, Chalobah, Sarr; Hudson-Odoi, Kovacic, Saul, Alonso (c); Ziyech, Havertz, Barkley.

Subs: Bettinelli, Sharman-Lowe, Chilwell, Rudiger, Thiago Silva, Jorginho, Mount, Vale.

Southampton: Forster, Valery, Lyanco, Salisu, Walker-Peters, S.Armstrong (c), Diallo, Tella, Djenepo, A.Armstrong, Adams.

Subs: Lewis, Bednarek, Livramento, Smallbone, Perraud, Romeu, Redmond, Walcott, Long.

The referee is Kevin Friend.

Remember, you can now edit your Play Predictor submissions up to just five minutes before kick-off. Now you know who's playing, it's time to make your prediction for the first goal scorer on The 5th Stand app!