For our third Women’s Champions League game of the season, Emma Hayes makes three changes from the 3-0 WSL win over Spurs at the weekend.
Fran Kirby returns to the line-up and there is a start for Johanna Rytting Kaneryd with Jessie Fleming and Lauren James making way. Niamh Charles is restored on the right of defence in place of Eve Perisset.
Pernille Harder is out long term following hamstring surgery.
Ashanti Akpan, from the Chelsea youth system, is named among the substitutes.
Real Madrid name former Man City and current Scotland international attacker Caroline Weir in their line-up.
Chelsea: Berger; Charles, Buchanan, Bright, Eriksson (c), Cuthbert, Ingle, Rytting Kaneryd, Kirby, Reiten, Kerr.
Subs: Musovic, Abdullina, Carter, Perisset, Nouwen, Akpan, Cankovic, Fleming, James, Svitkova, England.
Real Madrid: Rodriguez; Kenti Robles, Sousa, Andres (c), Carmona, Zornoza, Olofsson, Maite Oroz, Weir, Gonzalez, Feller.
Subs: Gerard, Fuente, Abelleira, Rocio Galvez, Nahikari Garcia, Toletti, Claudia Florentino, Moller, Lucia Rodriguez, Del Castillo, Svava, Camacho.
The referee is Maria Sole Caputi from Italy.
The game will be live streamed on The 5th Stand and chelseafc.com