For the 200th WSL selection with Emma Hayes as manager, she makes seven changes to the side that started Sunday’s FA Cup semi-final.
Only Hannah Hampton in goal, and Jess Carter, Kadeisha Buchanan and Niamh Charles in defence, retain their places. League ever-present Charles is today’s captain.
After eight substitute appearances, Catarina Macario makes her first start and is joined in the attack by Fran Kirby, Aggie Beever-Jones and Maika Hamano.
Sophie Ingle and Sjoeke Nusken come into midfield and there is a place for Ashley Lawrence at the back.
The Aston Villa side shows three changes from their draw against Leicester in their most recent game.
Chelsea Hampton; Lawrence, Carter, Buchanan, Charles (c), Ingle, Nusken, Beever-Jones, Kirby, Hamano, Macario
Subs Musovic, Perisset, Cuthbert, Leupolz, Reiten, Rytting Kaneryd, Ramirez
Aston Villa Leat; Maritz, Patten, Corsie (c), Mayling, Taylor, Nobbs, Dali, Magill, Daly, Salmon
Subs Gregory, Hanson, Poor, Leon, Lehmann, Mullett
Referee Melissa Burgin