Madueke is one of three fresh faces in attacking positions. Cole Palmer returns after suspension and Armando Broja is given a start. Nicolas Jackson retains his place with Mykhailo Mudryk, Christopher Nkunku and Ian Maatsen on the bench.

The other change is in defence where Thiago Silva comes in for Benoit Badiashile, who is not involved.

Malo Gusto, Axel Disasi and Levi Colwill complete the backline. Conor Gallagher and Moises Caicedo are again the central midfielders.

Enzo Fernandez is fit enough to return to the bench, joined there by Mudryk, Nkunku and Raheem Sterling.

Chelsea: Petrovic, Gusto, Disasi, Thiago Silva, Colwill, Caicedo, Gallagher (c), Madueke, Palmer, Jackson, Broja.

Subs: Bettinelli, Bergstrom, Maatsen, Gilchrist, Enzo, Matos, Mudryk, Nkunku, Sterling

Luton: Kaminski, Mengi, Osho, Bell (c), Kabore, Barkley, Lokonga, Doughty, Townsend, Brown, Adebayo

The referee is Paul Tierney.